Fifth Disease

The video shows a boy with Fifth Disease. Typical symptoms for this childhood disease include fever and rash on the cheeks.

What is...

What is fifth disease?

Fifth disease is a viral infection that causes mild fever and a characteristic "slapped-cheek" rash.

It is most common among school-aged children, but also can affect adults. Fortunately, about half of all adults have already had this disease and cannot get it again.

A virus called Parvovirus B19 causes fifth disease, also called erythema infectiosum. It is spread from person-to-person when there is direct contact with fluids or mucus from the nose or mouth of someone infected with it.

The time period from infection until symptoms begin (the incubation period) is usually 4 to 14 days, but may be as long as three weeks.

Symptoms

Symptoms and signs

Fifth disease typically begins with a little fever, maybe some headache and cold symptoms (runny nose sore throat, and cough).

These symptoms may last for a few days before the rash appears on the face, with blushing in the cheeks. The cheeks look bright red, as if they have been "slapped."

After some days, a lacy red rash may spread down the body, often seen best on the arms and legs but the palms of the hands and the soles of the feet are usually spared. The rash, which is itchy for some children, lasts from 1 to 3 weeks. Once in a while, the rash may become more noticeable due to exposure to sunlight, heat or physical activity. 

Other symptoms and signs can include swollen lymph glands, red eyes, sore throat and diarrhea. In many patients, fifth disease may not cause any symptoms at all.

Complications

Complications

Fifth disease is often mild and seldom leads to complications.

Among older children and adults, pain and swelling in the hands, wrists, ankles and knees may occur. These joint problems go away on their own, but may last for a few months.

Children with lowered immune defenses (for example, children with cancer or AIDS) or blood diseases such as sickle cell anemia, can become seriously ill with fifth disease because this virus slows the number of red blood cells that are made.

In addition, pregnant women who become infected can pass this virus to their fetus, which in very rare cases, can lead to problems in the fetus, stillbirth or miscarriage.

Home treatment

Treatment / What you should do

A child with fifth disease usually has minimal if any discomfort. Treat their symptoms as necessary.

Rest and lots of liquids will help with any cold symptoms. Anti-itch medications like the antihistamine diphenhydramine (Benadryl) may be helpful if the rash is itchy. Acetaminophen can be given if fever or joint pains occur. Antibiotics are not helpful because a virus causes fifth disease.

Prevention

It is difficult to avoid infection with fifth disease, as infection usually is spread before the rash breaks out.

Once a person has the rash, he is no longer contagious. Covering your mouth when you cough or sneeze, frequent hand washing, cleansing of toys, and avoiding contact with people who are sick, can all help decrease the chances of developing viral illnesses.

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Fifth Disease
Fifth Disease

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